Hoof and Mouth Disease...this is bizarre!

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This is bizarre! Evidently, Hoof and Mouth disease isn't even deadly. It appears the Europeans (and the rest of the world) are vastly over reacting...especially when one considers how they have under-reacting to Mad Cow, a truly deadly, human-endangering disease. What is going on with all this killing off of Cows, Sheep and Pigs?

56 cases confirmed in the plague that never was

Foot and mouth should not be a crisis. We have all been misled by the men from the ministry

By Geoffrey Lean

4 March 2001

This weekend – as funeral pyres light up the night sky and barriers go up all over Britain's broad acres – farming and the countryside face their biggest crisis, and their greatest opportunity, since the Second World War.

56 cases confirmed in the plague that never was

Foot and mouth should not be a crisis. We have all been misled by the men from the ministry

By Geoffrey Lean

4 March 2001

This weekend – as funeral pyres light up the night sky and barriers go up all over Britain's broad acres – farming and the countryside face their biggest crisis, and their greatest opportunity, since the Second World War.

Yet – despite the draconian measures – foot and mouth is a mild disease, from which animals recover naturally and quickly. It has only been turned into a disaster by the heedless intensification of agriculture over the past 50 years.

By today - after confirmation of three new cases, one in Devon and two in Tyne and Wear - 56 herds had caught the disease. Yesterday saw the largest rise in cases in a single day, with 45,000 cows, sheep and pigs had been slaughtered to try to stop it spreading. And Britain had a Keep Out countryside. Every footpath in every national park is closed, as are all but 20 of the National Trust's properties, and all two-and-a-half million acres of the Forestry Commission's land.

Fixtures from the Wales v Ireland rugby match to Crufts have been cancelled. The farming industry, already on its knees, is staring into the abyss and neighbouring nations wait – with fear and fury mixed – to see how they will be affected. The crisis has severely shaken Tony Blair, and, as senior ministers confirmed yesterday, forced him to abandon his plans to announce the General Election for 5 April immediately after Wednesday's Budget.

The disease's escalating effects, the draconian control measures and the unanimously sombre tone of commentators, all suggest that the country must be facing a devastating killer plague.

But we aren't. Foot and mouth disease only very rarely affects people, and even then only raises a slight temperature and a few blisters. It doesn't even kill animals.

As the Ministry of Agriculture, Fisheries and Food (MAFF) itself admits, the sheep, pigs and cows being slaughtered and burned would shake it off in two or three weeks if they were allowed to live. Vets say that it is no more serious for animals than a bad cold for humans.

Instead, it is an economic disease. When animals are sick they produce less milk, and put on less meat. MAFF asserts that cows also milk less well when they recover, though late last week could produce no scientific evidence to prove it.

Yet MAFF steadfastly refuses to countenance any relaxation of its zero tolerance policy. This contrasts sharply with the enormous tolerance it showed BSE, allowing hundreds of thousands of diseased animals into the food chain and permitting controls – when introduced – to be poorly enforced and widely flouted.

Yet BSE really is a terrifying plague which has killed 80 people, slowly and horrifically, and will do the same to thousands, maybe hundreds of thousands, more over coming decades.

MAFF's reaction to the two diseases shows where its priorities lie. It cares little for human health. It is not even particularly bothered about sick animals. What gets it exercised, and spurs it to emergency action, is a threat to the profitability of agribusiness.

In a sane world, the economic losses caused by this mild disease would not matter much: farmers would accept and adjust to them, as to the fluctuations of their harvests. But the crazy overintensification of agriculture, with margins pared to the bone to produce cheap food against foreign competition, means it simply cannot afford them.

Britain pioneered the intensification on this side of the Atlantic. No European country has pursued it so relentlessly, or has so ruthlessly driven small farmers to the wall to benefit richer ones: more than 330,000 farms – two-thirds of the total – have been forced out of business since 1945.

Abigail Woods – a vet who is researching the history of foot and mouth at Manchester University, financed by the Wellcome Trust – adds that it was Britain, too, that pioneered the zero tolerance policy to foot and mouth, originally to protect a few wealthy stockbreeders, and was the first country to ban imports from countries with the disease.

Now, hoist with its own petard, MAFF has no alternative but to continue the slaughter to stop British meat being excluded from export markets that have followed our lead. Intensification may not be to blame for the outbreak of the disease, but it has turned it into a crisis affecting the highest in the land.

Mr Blair – who on Tuesday makes his second green speech in less than six months after more than three years of silence – told a private Downing Street meeting of environmentalists and businessmen on Thursday that the floods, the collapse of agriculture and the latest scientific predictions on the effects of global warming (reported in the Independent on Sunday last month) showed we were now reaping the harvest of past neglect.

All this may be providing a catalyst for change. Tony Blair has called for a national debate on the future of agriculture. Ministers accept that policies of the past decades have failed and are cautiously moving towards a radical shift – from intensifying agriculture to preserving the environment as the basis of sound farming.

They want to switch the bulk of the massive subsidies given to agriculture from intensifying production to conserving and managing the countryside. And they say that the foot and mouth emergency is speeding up the process.

They face two obstacles. The first is the European Union, which, led by France and Germany, has resisted change. But Germany appointed a new Green agriculture minister in the crisis that followed the discovery of BSE in the country. She has indicated that Germany will join the campaign for reform. If it does, ministers believe they could muster the votes to push it through.

The second, much more formidable obstacle is MAFF, which is responsible for the mess in the first place and has lost none of its conservatism or obscurantism.

It must be allowed to obstruct no more. When the last glows of the burnt carcasses have died away, ministers must build one more pyre – for MAFF itself, and the whole misguided set of entrenched interests it represents.

56 cases confirmed in the plague that never was

Foot and mouth should not be a crisis. We have all been misled by the men from the ministry

By Geoffrey Lean

4 March 2001

This weekend – as funeral pyres light up the night sky and barriers go up all over Britain's broad acres – farming and the countryside face their biggest crisis, and their greatest opportunity, since the Second World War.

Yet – despite the draconian measures – foot and mouth is a mild disease, from which animals recover naturally and quickly. It has only been turned into a disaster by the heedless intensification of agriculture over the past 50 years.

By today - after confirmation of three new cases, one in Devon and two in Tyne and Wear - 56 herds had caught the disease. Yesterday saw the largest rise in cases in a single day, with 45,000 cows, sheep and pigs had been slaughtered to try to stop it spreading. And Britain had a Keep Out countryside. Every footpath in every national park is closed, as are all but 20 of the National Trust's properties, and all two-and-a-half million acres of the Forestry Commission's land.

Fixtures from the Wales v Ireland rugby match to Crufts have been cancelled. The farming industry, already on its knees, is staring into the abyss and neighbouring nations wait – with fear and fury mixed – to see how they will be affected. The crisis has severely shaken Tony Blair, and, as senior ministers confirmed yesterday, forced him to abandon his plans to announce the General Election for 5 April immediately after Wednesday's Budget.

The disease's escalating effects, the draconian control measures and the unanimously sombre tone of commentators, all suggest that the country must be facing a devastating killer plague.

But we aren't. Foot and mouth disease only very rarely affects people, and even then only raises a slight temperature and a few blisters. It doesn't even kill animals.

As the Ministry of Agriculture, Fisheries and Food (MAFF) itself admits, the sheep, pigs and cows being slaughtered and burned would shake it off in two or three weeks if they were allowed to live. Vets say that it is no more serious for animals than a bad cold for humans.

Instead, it is an economic disease. When animals are sick they produce less milk, and put on less meat. MAFF asserts that cows also milk less well when they recover, though late last week could produce no scientific evidence to prove it.

Yet MAFF steadfastly refuses to countenance any relaxation of its zero tolerance policy. This contrasts sharply with the enormous tolerance it showed BSE, allowing hundreds of thousands of diseased animals into the food chain and permitting controls – when introduced – to be poorly enforced and widely flouted.

Yet BSE really is a terrifying plague which has killed 80 people, slowly and horrifically, and will do the same to thousands, maybe hundreds of thousands, more over coming decades.

MAFF's reaction to the two diseases shows where its priorities lie. It cares little for human health. It is not even particularly bothered about sick animals. What gets it exercised, and spurs it to emergency action, is a threat to the profitability of agribusiness.

In a sane world, the economic losses caused by this mild disease would not matter much: farmers would accept and adjust to them, as to the fluctuations of their harvests. But the crazy overintensification of agriculture, with margins pared to the bone to produce cheap food against foreign competition, means it simply cannot afford them.

Britain pioneered the intensification on this side of the Atlantic. No European country has pursued it so relentlessly, or has so ruthlessly driven small farmers to the wall to benefit richer ones: more than 330,000 farms – two-thirds of the total – have been forced out of business since 1945.

Abigail Woods – a vet who is researching the history of foot and mouth at Manchester University, financed by the Wellcome Trust – adds that it was Britain, too, that pioneered the zero tolerance policy to foot and mouth, originally to protect a few wealthy stockbreeders, and was the first country to ban imports from countries with the disease.

Now, hoist with its own petard, MAFF has no alternative but to continue the slaughter to stop British meat being excluded from export markets that have followed our lead. Intensification may not be to blame for the outbreak of the disease, but it has turned it into a crisis affecting the highest in the land.

Mr Blair – who on Tuesday makes his second green speech in less than six months after more than three years of silence – told a private Downing Street meeting of environmentalists and businessmen on Thursday that the floods, the collapse of agriculture and the latest scientific predictions on the effects of global warming (reported in the Independent on Sunday last month) showed we were now reaping the harvest of past neglect.

All this may be providing a catalyst for change. Tony Blair has called for a national debate on the future of agriculture. Ministers accept that policies of the past decades have failed and are cautiously moving towards a radical shift – from intensifying agriculture to preserving the environment as the basis of sound farming.

They want to switch the bulk of the massive subsidies given to agriculture from intensifying production to conserving and managing the countryside. And they say that the foot and mouth emergency is speeding up the process.

They face two obstacles. The first is the European Union, which, led by France and Germany, has resisted change. But Germany appointed a new Green agriculture minister in the crisis that followed the discovery of BSE in the country. She has indicated that Germany will join the campaign for reform. If it does, ministers believe they could muster the votes to push it through.

The second, much more formidable obstacle is MAFF, which is responsible for the mess in the first place and has lost none of its conservatism or obscurantism.

It must be allowed to obstruct no more. When the last glows of the burnt carcasses have died away, ministers must build one more pyre – for MAFF itself, and the whole misguided set of entrenched interests it represents.

Yet – despite the draconian measures – foot and mouth is a mild disease, from which animals recover naturally and quickly. It has only been turned into a disaster by the heedless intensification of agriculture over the past 50 years.

By today - after confirmation of three new cases, one in Devon and two in Tyne and Wear - 56 herds had caught the disease. Yesterday saw the largest rise in cases in a single day, with 45,000 cows, sheep and pigs had been slaughtered to try to stop it spreading. And Britain had a Keep Out countryside. Every footpath in every national park is closed, as are all but 20 of the National Trust's properties, and all two-and-a-half million acres of the Forestry Commission's land.

Fixtures from the Wales v Ireland rugby match to Crufts have been cancelled. The farming industry, already on its knees, is staring into the abyss and neighbouring nations wait – with fear and fury mixed – to see how they will be affected. The crisis has severely shaken Tony Blair, and, as senior ministers confirmed yesterday, forced him to abandon his plans to announce the General Election for 5 April immediately after Wednesday's Budget.

The disease's escalating effects, the draconian control measures and the unanimously sombre tone of commentators, all suggest that the country must be facing a devastating killer plague.

But we aren't. Foot and mouth disease only very rarely affects people, and even then only raises a slight temperature and a few blisters. It doesn't even kill animals.

As the Ministry of Agriculture, Fisheries and Food (MAFF) itself admits, the sheep, pigs and cows being slaughtered and burned would shake it off in two or three weeks if they were allowed to live. Vets say that it is no more serious for animals than a bad cold for humans.

Instead, it is an economic disease. When animals are sick they produce less milk, and put on less meat. MAFF asserts that cows also milk less well when they recover, though late last week could produce no scientific evidence to prove it.

Yet MAFF steadfastly refuses to countenance any relaxation of its zero tolerance policy. This contrasts sharply with the enormous tolerance it showed BSE, allowing hundreds of thousands of diseased animals into the food chain and permitting controls – when introduced – to be poorly enforced and widely flouted.

Yet BSE really is a terrifying plague which has killed 80 people, slowly and horrifically, and will do the same to thousands, maybe hundreds of thousands, more over coming decades.

MAFF's reaction to the two diseases shows where its priorities lie. It cares little for human health. It is not even particularly bothered about sick animals. What gets it exercised, and spurs it to emergency action, is a threat to the profitability of agribusiness.

In a sane world, the economic losses caused by this mild disease would not matter much: farmers would accept and adjust to them, as to the fluctuations of their harvests. But the crazy overintensification of agriculture, with margins pared to the bone to produce cheap food against foreign competition, means it simply cannot afford them.

Britain pioneered the intensification on this side of the Atlantic. No European country has pursued it so relentlessly, or has so ruthlessly driven small farmers to the wall to benefit richer ones: more than 330,000 farms – two-thirds of the total – have been forced out of business since 1945.

Abigail Woods – a vet who is researching the history of foot and mouth at Manchester University, financed by the Wellcome Trust – adds that it was Britain, too, that pioneered the zero tolerance policy to foot and mouth, originally to protect a few wealthy stockbreeders, and was the first country to ban imports from countries with the disease.

Now, hoist with its own petard, MAFF has no alternative but to continue the slaughter to stop British meat being excluded from export markets that have followed our lead. Intensification may not be to blame for the outbreak of the disease, but it has turned it into a crisis affecting the highest in the land.

Mr Blair – who on Tuesday makes his second green speech in less than six months after more than three years of silence – told a private Downing Street meeting of environmentalists and businessmen on Thursday that the floods, the collapse of agriculture and the latest scientific predictions on the effects of global warming (reported in the Independent on Sunday last month) showed we were now reaping the harvest of past neglect.

All this may be providing a catalyst for change. Tony Blair has called for a national debate on the future of agriculture. Ministers accept that policies of the past decades have failed and are cautiously moving towards a radical shift – from intensifying agriculture to preserving the environment as the basis of sound farming.

They want to switch the bulk of the massive subsidies given to agriculture from intensifying production to conserving and managing the countryside. And they say that the foot and mouth emergency is speeding up the process.

They face two obstacles. The first is the European Union, which, led by France and Germany, has resisted change. But Germany appointed a new Green agriculture minister in the crisis that followed the discovery of BSE in the country. She has indicated that Germany will join the campaign for reform. If it does, ministers believe they could muster the votes to push it through.

The second, much more formidable obstacle is MAFF, which is responsible for the mess in the first place and has lost none of its conservatism or obscurantism.

It must be allowed to obstruct no more. When the last glows of the burnt carcasses have died away, ministers must build one more pyre – for MAFF itself, and the whole misguided set of entrenched interests it represents.

-- meg davis (meg9999@aol.com), March 05, 2001

Answers

Great article Meg! Add to this plague that never was: AIDS. Read Peter Duesberg's book, Inventing the Aids Virus. Or read one authored by a Brittish woman, Joan Shenton, Positively False. HIV is not killing anyone (sort of like hoof and mouth), but look how we have totally overreacted (treatment with AZT DOES KILL). We need to seriously consider what the world health organization (WHO) has as their underlying objective for humanity in general. Throw in the FDA/USDA/NIH (national institute of health). They seem to all be in this together. So now the world's delicate over-taxed food supply is smashed and many will actually believe we would all have died of "aids" anyway.

-- ken (n4wind@aol.com), March 06, 2001.

Hey Doc, I aint got no aids. Its all just a conspiracy.

06/03/2001 13:27 - (SA) A doctor's hope: one day without HIV

Pretoria – “If only I could have one day in which I don't have to diagnose a new patient HIV-positive, I would be happy.”

Dr Mandlalele Mhinga sits in his consulting rooms across the road from the Chris Hani-Baragwanth Hospital in Soweto. In front of his rooms row upon row of mini bus taxis wait for passengers. It is a surging, busy urban environment.

In Mhinga’s rooms patients come and go. Some stand talking, others sit quietly, waiting for their turn, while posters on the wall proclaim messages about diseases like diabetes, hepatitis, flu vaccinations, acne and skin care.

And, of course, HIV/Aids. You cannot contract Aids through contact with crockery and cutlery, by donating blood, by using a toilet, through insect bites or by visiting other people, reads the message on one poster. The disease is mainly spread through sex. Therefore: Be faithful. Use condoms.

But at least once a day it is Mhinga’s thankless task to inform a patient that their blood test results have come back, and yes, the result is positive. A few years ago he had to break the news no more than once every two-to-three weeks.

And that's only new patients. Amongst the 40 patients he examines every day, there are at least two or three who have tested HIV positive previously.

Aids has already claimed some of his patients' lives this year.

Mhinga, who is married to well-known singer Yvonne Chaka Chaka, tells of a woman who was diagnosed with HIV five years ago.

Initially healthy, she deteriorated gradually. She stopped working early last year and by March she had to use a cane to walk. “A month or so ago she arrived at my rooms in a wheelchair.” She was tired, she said. She wanted to lie down on the examination table. Mhinga says if he had allowed her to, she would have died then and there. There was barely life left in her.

The next morning her family sent news of her death.

Mhinga is a gentle person. He speaks in a soft tone and cases like this clearly upset him. He often has to mediate between patients and their families.

Another patient was HIV positive for six years and steadfastly refused to inform anyone of her status, including her daughter and sister.

Mhinga asked them to visit to his rooms. When they were all together, he asked the patient whether she wanted to convey the news herself, or whether he should do it. The women then looked her daughter in the eye and told her – whereupon the daughter embraced her mother, telling her that she had known all along. Her mother’s physical appearance had given her away.

Since then, Mhinga said, the woman’s condition has improved markedly. She is eating well, she has gained weight, she even returned to work – probably because she now has her family's emotional support. But a year ago she was convinced she was dying.

Emotional support, Mhinga maintains, is very important. That's why he doesn't wear gloves when he examines his patients. In touching them with his bare hands he shows them that they are acceptable. He will, at times, take a patient in his arms to comfort them if necessary.

Mhinga claims attitudes towards HIV/Aids have improved. People are much more open and will talk more readily about the disease. During funerals over the weekends – and there are many funerals over weekends – an announcement is made if the deceased had Aids.

He also believes that information and education campaigns are reaching people. The condom strategy is also paying off.

He tells of an HIV-positive patient who recently arrived at his rooms with her new boyfriend for a test. He tested HIV-negative.

The couple are using condoms and Mhinga says he is certain if the boyfriend were to be re-tested in six months’ time the test would return negative, as his experience with similar couples has shown.

However, there remains a certain amount of ignorance regarding HIV/Aids. Mhinga’s chooses his words with care: “If there are still people who believe they can be cured by abusing children, stop it – it is a myth.”

He deals with girls who have been abused by men seeking a "cure". They have been raped by family members in the belief they would be “purified” of the virus by having sex with a virgin.

But the battle against Aids is not lost. One encouraging aspect of the issue for Mhinga is in helping someone with the virus to stay healthy. He maintains the most important factor is following a healthy diet with a regimen of vitamin supplements. HIV-positive people should also avoid risky behaviour such as drinking and smoking and should exercise regularly.

Without expensive drug treatment, he is helping several HIV-positive patients to lead a normal life by following this routine. Among them is a person who has been HIV-positive for 12 years and remains healthy.

Poor patients struggle to maintain a healthy diet, which is why poverty is an important factor in the HIV/Aids battle. “People suffering from malnutrition do not have a good chance of survival,” he said.

However, he remains positive in dealing with his patients, no matter how high the HIV/Aids mountain. "You can never give up hope. A cure for Aids might well be discovered within the next six months or a year," he says

Although, he says, he would be grateful for just one day without having to tell a new patient he or she has tested HIV positive.

http://news.24.com/News24/Health/Aids_Focus/0,1113,2-14- 659_991372,00.html



-- Martin Thompson (mthom1927@aol.com), March 06, 2001.


Who is stealing all the money? There is no aids in Kenya.

Panafrican News Agency (Dakar)

March 5, 2001 Posted to the web March 5, 2001

Nairobi, Kenya

Kenya's annual income could be reduced by more than half due to the amount of government spending required to sustain the fight against HIV/AIDS, a local organisation intimated Monday.

The Kenya National AIDS Control Council (KNACC) said that the country's 180 billion Kenyan shillings (about 2.3 billion US dollars) annual income could be reduced to 73 billion shillings (about 900 million dollars) if preventive measures were not put in place.

KNACC chairman Dr Mohammed Abdalla made the observation when he addressed a workshop on the management of HIV/AIDS in the town of Kericho.

With an average of 200 Kenyans dying of AIDS daily, he said Kenya ranks ninth in Africa with 2.2 million AIDS patients.

In Kisumu, he noted, several homesteads along Lake Victoria have been wiped out by the scourge.

Participants at the workshop petitioned the Government to urgently introduce family life education in schools.

Elsewhere, the chairman for Kakamega County Council chairman, Johnstone Andambi, affirmed that half of AIDS deaths in the area occur among people aged between 18 and 40 years.

In neighbouring Homabay area of the Lake Victoria region, district education officer, Beatrice Adhu, urged play directors and producers to use theatre to educate the youth on the dangers of HIV/AIDS.

She was speaking at Homa Bay High School while closing a drama festival for the district's secondary schools.

-- Martin Thompson (mthom1927@aol.com), March 06, 2001.


AIDS is real. Whether or not HIV has anything to do with it is what is in dispute:

article: Note: Dr. Mullis was awarded the 1993 Nobel Prize in Chemistry. This article is excerpted from his forthcoming book, Dancing Naked in the Mind Field, to be published by Pantheon.

When I {Kary Mullis] first heard in 1984 that Luc Montagnier of France's Pasteur Institute and Robert Gallo of America's National Institutes of Health had independently discovered that the retrovirus H.I.V. -- human immunodeficiency virus -- caused AIDS, I accepted it as just another scientific fact. It was a little out of my field of biochemistry, and these men were specialists in retroviruses.

Four years later I was working as a consultant at Specialty Labs in Santa Monica. Specialty was trying to develop a means of using P.C.R. [polymerase chain reaction, a D.N.A.-amplification method conceived by Mullis] to detect retroviruses in the thousands of blood donations received per day by the Red Cross. I was writing a report on our progress for the project sponsor, and I began by stating, "H.I.V. is the probable cause of AIDS."

I asked a virologist at Specialty where I could find the reference for H.I.V. being the cause of AIDS.

"You don't need a reference," he told me. "Everybody knows it."

"I'd like to quote a reference." I felt a little funny about not knowing the source of such an important discovery. Everyone else seemed to.

"Why don't you cite the C.D.C. report?" he suggested, giving me a copy of the Centers for Disease Control's periodic report on morbidity and mortality. I read it. It wasn't a scientific article. It simply said that an organism had been identified -- it did not say how. It requested that doctors report any patients showing certain symptoms and test them for antibodies to this organism. The report did not identify the original scientific work, but that didn't surprise me. It was intended for physicians, who didn't need to know the source of the information. Physicians assumed that if the C.D.C. was convinced, there must exist real proof somewhere that H.I.V. was the cause of AIDS.

A proper scientific reference is usually a published article in a reliable scientific magazine. These days the magazines are on slick glossy paper with pictures on the front and lots of advertisements, a lot of editorial material by people who are professional journalists, and a few pictures of girls selling you things you might want to buy for your lab. The advertisers are the companies that make things for scientists to buy and the companies that make drugs for doctors to sell. Therefore there are no major journals without corporate connections.

Scientists submit the articles in order to report their work. Preparing articles describing their work and having them published is crucial to a scientist's career, and without articles in major journals they will lose their rank. The articles may not be submitted until experiments supporting the conclusions drawn are finished and analyzed. In primary journals every single experimental detail has to be there either directly or by reference, so that somebody else can repeat exactly what was done and find out whether it comes out the same way in their hands. If it doesn't, somebody will report that, and the conflict eventually has to be resolved so that when we go on from here we know where "here" is. The most reliable primary journals are refereed. After you send in your article, the editors send copies of it to several of your colleagues for review. They become the referees.The editors are paid for their work on the journal; the colleagues are not. But what they do gives them power, which most of them like.

I did computer searches. Neither Montagnier, Gallo, nor anyone else had published papers describing experiments which led to the conclusion that H.I.V. probably caused AIDS. I read the papers in Science for which they had become well known as AIDS doctors, but all they had said there was that they had found evidence of a past infection by something which was probably H.I.V. in some AIDS patients. They found antibodies. Antibodies to viruses had always been considered evidence of past disease, not present disease. Antibodies signaled that the virus had been defeated. The patient had saved himself. There was no indication in these papers that this virus caused a disease. They didn't show that everybody with the antibodies had the disease. In fact they found some healthy people with antibodies.

If Montagnier and Gallo hadn't really found this evidence, why was their work published, and why had they been fighting so hard to get credit for the discovery? There had been an international incident wherein Robert Gallo of the N.I.H. had claimed that his own lab had not been able to grow the virus from the sample sent to him by Luc Montagnier in Paris. The virus he was able to grow, he said, came from samples collected at his end from putative AIDS patients. Gallo had patented the AIDS test based on these samples, and the Pasteur Institute had sued. The Pasteur eventually won, but back in 1989 it was a standoff, and they were sharing the profits.

I was hesitant to write "H.I.V. is the probable cause of AIDS" until I found published evidence that would support it. Mine was the most minimal statement possible. In my progress report I wasn't trying to say that it absolutely did cause AIDS, I was just trying to say that it was likely to cause it for some known reasons. Tens of thousands of scientists and researchers were spending billions of dollars a year doing research based on this idea. The reason had to be there somewhere; otherwise these people would not have allowed their research to settle into one narrow channel of investigation.

I lectured about P.C.R. at innumerable meetings. Always there were people there talking about H.I.V. I asked them how it was that we knew H.I.V. was the cause of AIDS. Everyone said something. Everyone had the answer at home, in the office, in some drawer. They all knew, and they would send me the papers as soon as they got back. But I never got any papers. Nobody ever sent me the news about how AIDS was caused by H.I.V.

I finally had the opportunity to ask Dr. Montagnier about the reference when he lectured in San Diego at the grand opening of the U.C.S.D. AIDS Research Center, which is still run by Bob Gallo's former consort, Dr. Flossie Wong-Staal. This would be the last time I would ask my question without showing anger. In response Dr. Montagnier suggested, "Why don't you reference the C.D.C. report?"

"I read it," I said. "That doesn't really address the issue of whether or not H.I.V. is the probable cause of AIDS, does it?"

He agreed with me. It was damned irritating. If Montagnier didn't know the answer, who the hell did?

[....] -----------

It's not exactly a conspiracy. A hundred+ years ago, the southern US was plagued with pellagra. It was a devastating disease, obviously contagious (if one member of a family developed it, the others usually followed); sufferers were sent to sanatoria, where they were treated with the most potent medicines of the day (largely arsenic-based) in an effort to save them.

In 1915, a doctor noticed a strange pattern in a poor southern orphanage: the youngest children, still regarded as babies and fed fresh milk products, had no pellagra. The oldest group, old enough to help work and fed fresh meat, had none. The middle group, 6-11 years old, had neither meat nor milk owing to the limited budget. Some of *them* developed pellagra. This doctor (name escapes me) experimented on convicts (you could do that in those days): the ones kept on an ordinarydiet stayed healthy; the group deprived of meat and dairy developed pellagra. When their diets were returned to normal, the pellagra went away.

He published, and was railroaded out of medicine as a "flat earther" who was denying the truth of the new germ theory of disease -- never mind that the medical establishment already knew good and well what, say, scurvy was. Not till 1930 was pellagra recognized as a vitamin-B devficiency.

Kind of too bad for all those "treated" with arsenic medicines.

The argument today is similar: how can you effectively treat AIDS (which no one denies is a real, and real nasty, ailment) if you have not correctly nailed down its causation?

For the record, Dr. Mullis continues to speak out, at every opportunity, on his frustration at not finding ANY paper *scientifically* demonstrating that HIV *causes* AIDS.

Many things can cause a "false-positive" reading on an HIV test, including flu and having borne more than one child. Once you are HIV+, your (for example) tuberculosis is no longer "just" TB but AIDS and you are treated not with TB-specific medicine, but with the viciously-toxic (albeit not arsenic-based) AIDS drugs. Oddly, your chances of dying of AIDS are significantly higher (1:4 or 1:3) in Western countries with easy access to these drugs, than in Africa (1:15 or so).

Knowing the etiology is *vital*.

Can you imagine how embarrassed some of those old pellagra doctors must have felt?

-- L. Hunter Cassells (mellyrn@nist.gov), March 06, 2001.


ProMED Digest Tuesday, March 6 2001 Volume 2001 : Number 052

***************************************

Date: Mon, 5 Mar 2001 22:41:53 -0500 (EST) From: ProMED-mail Subject: PRO/AH> Foot & mouth disease, antiquated control

FOOT & MOUTH DISEASE, ANTIQUATED CONTROL ****************************************

A ProMED-mail post ProMED-mail, a program of the International Society for Infectious Diseases

Date: 4 Mar 2001 From: C.H. Calisher

Dr. D.A. Henderson and I have been chatting back and forth about foot-and-mouth disease (FMD). As always, he had a number of questions and comments and, as always, I could not answer them. Here is what he said, modified slightly by me as follows:

"It seems to me that with the enormous increase in movement of people and animals that takes place, the concept of controlling FMD by the elaborate rituals to assure FMD free countries is no longer tenable or appropriate. What is wrong with a vaccination program?

The cost per animal is surely not a limiting factor. The vaccine has to match a prevalent or likely-to-be-prevalent strain. We do this now with influenza. Is anyone investing significant effort to develop a more broadly antigenic vaccine?

I've always thought that the present approaches to FMD are antiquated but the implications of pursuing the present strategy look to me to be absolutely devastating."

My sentiments exactly. No matter what the International Committee on Taxonomy of Viruses says (i.e., that there is one FMD virus species and 7 serotypes of that single virus species), any of 7 viruses can cause FMD. It may be taxonomically sound to consider 7 viruses that do not cross-protect against each other as representing a single species, but it is counterproductive in practical terms. For example, if one immunizes against one serotype and then challenges the animal with that serotype and the animal withstands that challenge, that animal must be immune to that serotype. If one then challenges that animal with another serotype and that animal succumbs to infection with the second serotype, how can anyone say that the two serotypes are the same virus? Same species, sure, but not the same virus.

Given the broad and remarkable advances in modern studies of viral molecular genetics, why is it not possible to clone a conserved portion (possessed by all these viruses, else they would not be so closely related) of the genome of these viruses and prepare a vaccine against any and all of them? We ask this simply because we do not know the answer. Present vaccination programs appear to be based on vaccination against the specific serotype circulating in one place at one time. Surely topotypic variations cannot make much of a difference with respect to application of a vaccine comprised of a broadly cross-reactive antigen, one that would protect against all serotypes. Alternatively, if a DNA vaccine has not been considered, now would be the time to do so.

It is my own opinion/observation that research into the intricacies of FMD and the viruses that cause it likely has been inhibited by economics constraints as much as by intellectual ones. Markets for illegal sales of livestock is a world-wide problem. Hypocritical functionaries who look the other way when cattle are slaughtered or moved from their country to another country and slaughtered there, who look the other way when beef carcasses are moved by train, in broad daylight, from country to country, are known to function with impunity in the name of national sovereignty. Few countries are willing to stick their noses into the affairs of another country. So, disgusting traditions continue without hope for abatement and maintenance of "markets" are the sine qua non of the industry and of political goals.

Perhaps there is a need for a W.H.O.-type organization for livestock. Not an organization that counts bodies but a proactive organization, one that will send people to the problem area and assist the local authorities in making decisions and in taking actions.

The situation in England, and now elsewhere, is no different from the situations faced by other countries in other times. Is this story destined to be told again and again and again? Checking the shoes of walkers just does not seem to be the most enlightened of techniques for control of a disease, particularly when modern molecular methods are practically screaming to be applied. We ought all to reread Santayana.

- -- Charles H. Calisher, Ph.D. Department of Microbiology Colorado State University Fort Collins, Colorado, USA

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Date: Mon, 5 Mar 2001 22:27:47 -0500 (EST) From: ProMED-mail Subject: PRO/AH> Foot & mouth disease page on website

FOOT & MOUTH DISEASE PAGE ON WEBSITE

A ProMED-mail post ProMED-mail, a program of the International Society for Infectious Diseases

Date: 5 Mar 2001 From: ProMED-mail

This is to announce a new page on the ProMED-mail website:

Latest Foot and Mouth Information

Look for it on our Home Page at

It carries the most recent 20 posts on the outbreak from the e-mail list, so you have them all in one place.

- -- ProMED-mail

***************************************

-- Andre Weltman (aweltman@state.pa.us), March 06, 2001.



Sorry Dude, You've been had. Aids (30 different diseases we already have in conjunction with being tested positive for HIV (harmless)) is caused by environmental pollution. In Africa, the main culprit is Benzene (read Hulda Clark, Cure for all Disease). It's in their water supply from long term exposure to DDT and pesticides to control malaria. Many now have immune systems damaged beyond repair, and yes they are dying. Just not from anything caused by HIV. Once they get tested, they are literally quarantined away from further medication (like for the malaria they already had) since the doctors are so sure they are going to die anyway, why waste good medicine on a lowly "aids" patient.

-- ken (n4wind@aol.com), March 06, 2001.

Hulda Clark definately has had a colorful career.

The Bizarre Claims of Hulda Clark

Stephen Barrett, M.D. Hulda Regehr Clark, 71, claims to cure cancer, AIDS, and many other serious diseases. She describes herself as an "independent research scientist" with bachelor and master's degrees from the University of Saskatchewan and a Ph.D. degree in physiology from the University of Minnesota (1958). She also lists a naturopathic (N.D.) degree, but the source is not identified [1]. Her treatment is available at Century Nutrition, a clinic in Tijuana, Mexico, where the basic fee for two weeks of "treatment" is $4,500 (plus 10% tax). This figure does not include the cost of a motel room (approximately $210/week); meals ($250/week); blood tests ($70 each); standard diagnostic imaging tests ($40 to $400); dental x-rays (at least $206); "individually tailored" supplements ($400 to $1,500 for a month supply); equipment (about $350); tooth extractions ($80 each); and partial or full dentures ($450).

Bizarre Claims Clark claims that all cancers and many other diseases are caused by "parasites, toxins, and pollutants" and can be cured by killing the parasites and ridding the body of environmental chemicals. Her book The Cure for All Cancers states:

All cancers are alike. They are all caused by a parasite. A single parasite! It is the human intestinal fluke. And if you kill this parasite, the cancer stops immediately. The tissue becomes normal again. In order to get cancer, you must have this parasite. . . .

This parasite typically lives in the intestine where it might do little harm, causing only colitis, Crohn's disease or irritable bowel syndrome, or perhaps nothing at all. But if it invades a different organ, like the uterus, kidneys or liver, it does a great deal of harm. If it establishes itself in the liver, it causes cancer! It only establishes itself in the liver of some people. These people have propyl alcohol in their body. All cancer patients (100%) have both propyl alcohol and the intestinal fluke in their livers. The solvent propyl alcohol is responsible for letting the fluke establish itself in the liver. In order to get cancer, you must have both the parasite and propyl alcohol in your body [1:1-2].

Clark further alleges:

The adult fluke -- which she misspells as Faciolopsis buskii -- "stays stuck to our intestine, (or liver, causing cancer, or uterus, causing endometriosis, or thymus, causing AIDS, or kidney, causing Hodgkin's disease)." [1:4] Or the pancreas, causing diabetes; the brain, causing Alzheimer's disease; the prostate (causing prostatitis; or the skin if you have Kaposi's sarcoma [1:35]. As soon as there are adults in the liver. . . . a growth factor, called ortho-phospho-tyrosine appears. Growth factors make cells divide. Now YOUR cells will begin to divide too! Now you have cancer. . . . Having propyl alcohol in your body allows the fluke to develop outside of the intestine [1:8]. When the fluke and all its stages have been killed, the ortho-phospho- tyrosine is gone! Your cancer is gone [1:9]. Clearly, you must do 3 things: (1) Kill the parasite and all its stages; (2) stop letting propyl alcohol into your body; and (3) flush out the metals and common toxins from your body so you can get well [1:10]. It is not unusual for someone to have a dozen (or more) of the parasites I have samples of. You can assume that you, too, have a dozen different parasites [1:10]. Three herbs, used together, can rid you of over 100 types of parasites: black walnut hulls, wormwood, and common cloves [1:11-12]. But the amino acids ornithine and arginine improve this recipe [1:15]. Use of these five products will kill the cancer-causing fluke in the first five days and the remaining parasites in another two weeks [1:19]. It takes 5 days to be cured of cancer regardless of the type you have. Surgery, radiation, or chemotherapy can be canceled because, after Clark's recipe cures the cancer, it cannot come back [1:introductory passage]. All metal (fillings, crowns, bridges, etc.) should be removed from the mouth, and all teeth with root canals should be extracted, because their presence damages the immune system [1:46-48]. To prevent recurrence, stay on a maintenance program of killing parasites and give yourself a high-dose program at least twice a year. Also treat all family members and household pets [1:23-26]. All of the above notions are absurd. In a recent talk that attacked widespread misbeliefs about parasites, the president of the American Society of Parasitologists noted that if Clark's pseudoscientific claims were correct, "the medical establishment and . . . professional pathologists are guilty of a gigantic and cruel fraud on the public." [2]

Patients who "cleanse" their intestines with Clark's recommended herbs may excrete what they think are parasites. However, in one instance I know of, a specimen of "parasites" turned out to be citrus fibers, presumably from grapefruit juice used for the "cleanse."

Phony Devices Clark is also using and promoting two devices. Her Syncrometer is claimed to identify diseased organs and toxic substances by noting whether the device makes various sounds when "test substances" are placed on a plate [1:373-427]. The device is simply a galvanometer that measures skin resistance to a low-voltage current that passes from the device through a probe touched to the patient's hand. Various models for home use can either be commercially purchased or made by the patient. Clark's "Zapper" is a low-voltage device that supposedly kills parasites, bacteria, and viruses with electrical energy, but does not harm human tissue. Its use is based on Clark's notion that all living things broadcast a characteristic range of radio frequencies and that the device can issue counter-frequencies that kill unwanted organisms [3]. Neither device has any genuine diagnostic or therapeutic value.

Clark's books, herbal products, and "Zapper" devices said to be built to her specifications are marketed through many Web sites [A, B, C, D, E, F, G, H, I], one of which is the Self Help Resource Center, administered by Clark's son Geoff.

Her ideas are also advocated by the Dr. Clark Research Association, a group founded in 1998 by David P. Amrein, a Scientologist who describes himself as a freelance consultant in finance and taxes. Membership, which costs $40 per year, includes a subscription to the Dr. Clark Research Association Bulletin, which Amrein edits. The November 1999 issue stated that the Bulletin had a circulation of 1,500.

In November 1999, the Australian Competition and Consumer Commission announced that it had stopped an Australian company (Raylight Pty Ltd) from advertising that its "Parasite Zapper" passes an electric current through a person's blood and is effective against the AIDS virus, parasites, hepatitis, herpes, obesity, and other serious conditions. The company also agreed to provide refunds to consumers who felt they had been mislead [4].

Case Histories Pages 119-372 contain "case histories" of 138 cancer patients, of whom 103 were "cured" and 35 who "did not carry out instructions or could not be followed." The standard way to determine whether a treatment is effective is to carefully record the nature of the patient's disease before treatment and to determine the patient's condition indefinitely. Clark's reports contain little information about the patient's history and no indication that Clark performed any physical examinations. The only follow-up reports are for a few patients who returned for further treatment -- usually a few weeks later. Cancer treatment results are normally expressed in terms of cancer-free status or survival over periods of years. Five-year survival rates are a common measure. Clark claims she can tell that patients are cured as soon as their ortho-phospho-tyrosine test is negative -- within days or even a few hours after her treatment is begun. This claim is preposterous.

Thirty-eight of the 103 reports indicate that the patient had been medically diagnosed with cancer, and most of these 38 had received standard treatment. In 59 other cases, however, there was no indication that the patient had undergone any medical test or treatment that would indicate the presence of a cancer. (In 10 other cases, which Clark diagnosed as HIV infection, there was no history suggestive of AIDS. In the rest, it was not clear whether the patient had been medically diagnosed with cancer.)

Judging from the reports, Clark's judgments were based entirely on the results of her own peculiar diagnostic tests. If "ortho-phospho- tyrosine" was found in the blood, the patient had cancer. If a "protein 24 antigen" was found in the blood, the patient had AIDS. And, anywhere from a few hours to several weeks later, if these tests became negative, Clark considered the patient cured. The book describes how some of the patients who had consulted Clark for other problems were startled to hear they had cancer or AIDS.

None of the reports provides any basis for concluding that Clark's treatment has the slightest value. The majority of the people described in the 103 case reports did not have cancer. Of those that did, most had received standard medical treatment or their tumors were in their early stages. In these cases, Clark pronounced them cured but did not follow what happened after they left her clinic -- so she could not possibly know how they did afterward. In some cases, she counted patients as cured even though she noted that they died within a few weeks after she treated them.

Legal Trouble In September 1999, Clark was arrested in San Diego, California, based on a fugitive warrant from Indiana, where she faced charges of practicing medicine without a license. In November, a former patient filed suit accusing her of negligence and fraud.

The criminal case originated when Clark lived and practiced in Indiana [5,6]. In 1993, after a former patient complained to the Indiana attorney general, a health department official visited accompanied by a deputy attorney general visited her office and was diagnosed with AIDS and sent to a laboratory for a blood test [7]. Clark -- apparently tipped off by the lab -- found out she was being investigated and left Indiana a few days later. In 1999, Clark was apprehended in California and returned to Indiana to stand trial. However, in April 2000, an Indiana judge dismissed the charges on grounds that too much time had elapsed between the filing of the charges and Clark's arrest. The judge's verdict did not address the merits of the charges but only the issue of whether the delay had compromised Clark's ability to mount a defense and her right to a speedy trial [8].

The civil case was filed by Esther and Jose Figueroa of New York City against Clark, the Dr. Clark Research Association, Century Nutrition, and several associated individuals. Mrs. Figueroa, who had been medically diagnosed with breast cancer, sought treatment in September 1998. The court papers state that she was told:

Dust from her apartment was responsible for her breast cancer. Returning to her apartment would place her at special risk to develop leukemia because of her blood type. She had asbestos, lead, and a lot of copper in her system. The Syncrometer detected a parasite called "rabbit fluke" inside her breast. She also had E. coli, asbestos, and salmonella due to improper food sterilization. Several teeth should be removed and "cavitations" in her lower jaw should be scraped out. The suit also charges that

Clark subsequently arranged for all of Mrs. Figueroa's front and molar teeth to be removed, prescribed more than 30 dietary and herbal supplements to be taken during a 12-week period, and badly burned her breast while administering treatment with a "Zapper" device. During the 3-month period of treatment, the tumor increased from 1.5 cm to 14 cm. Despite this fact, Mrs. Figueroa was falsely told that she was getting better, that tests for "cancer markers" were negative, and that pain she was experiencing did not reflect persistence of her cancer. Libel Campaign Various Internet postings indicate that in September 1999, Hulda Clark's son, Geoffrey, hired Tim Bolen to assist her after she was arrested. Bolen and his wife Jan do business as JuriMed, an entity whose stated purpose is to assist "alternative" health practitioners faced with regulatory action, criminal prosecution, or other matters that threaten their financial well-being and/or license to practice. Bolen refers to JuriMed as a "public Relattions and Research Group." November 1999, the Bolens began distributing false and defamatory statements to the effect that:

I am arrogant, bizarre, closed-minded, emotionally disturbed, professionally incompetent, intellectually dishonest, a dishonest journalist, sleazy, unethical, a quack, a thug, a bully, a Nazi, a hired gun for vested interests, the leader of a subversive organization, and engaged in criminal activity (conspiracy, extortion, filing a false police report, and other unspecified acts). Terry Polevoy, M.D. (a Canadian pediatrician who operates anti- quackery Web sites) is dishonest, closed-minded, emotionally disturbed, professionally incompetent, unethical, a quack, a fanatic, a Nazi, a hired gun for vested interests, and engaged in criminal activity (conspiracy, stalking of females, and other unspecified acts) and has made anti-Semitic remarks. Attorney Grell (who represents Esther and Jose Figueroa in their suit against Hulda Clark) is professionally incompetent and has filed a false report with the FBI. Many of the messages were republished (sometimes with embellishment) on Web sites, in news group postings, and in other e-mail messages -- by other Clark allies and supporters.

After Clark's arrest, a defense fund was established to pay for expenses associated with defending her against "legal attacks." A description of the fund states that the covered expenses would include attorney fees, publicists, expert witnesses, court costs, and appeals and that Goeffrey Clark would administer the money without compensation. The report also stated that by May 31, 2000, the fund had raised $113,943.76, earned interest of $665.96, and spent $27,900.51 for legal expense, $327.65 for "Acct/Copies," $56,408.43 for public relations, and $714.30 for Hulda Clark's travel. It did not indicate how much of the public relations payment went to the Bolens.

In October 2000, I filed suit in my local court against Joseph Mercola, M.D., of Shaumberg, Illinois [9]. In November 2000, Attorney Grell, Dr. Polevoy and I filed suit in California against Hulda Clark, the Bolens, Jurimed, David Amrein, the Dr. Clark Association, and others who have spread or conspired to spread the defamatory messages [10].

More Legal Trouble? On February 16, 2001, Mexican authorities inspected Century Nutrition and ordered it to shut down. According to a report in the San Diego Union Tribune, the clinic had never registered.and was operating without a license. The article stated that authorties planned to review the matter and reach a final decision within a few days [11].

For Additional Information A Response to Clark's "Publicist" A Visit to Clark's Mexican Clinic (1996) Why the Sychrometer Is a Useless Tool Interview of Dr. Clark Three Days of Training with Dr. Clark Zapper Home Page Finding the Way: Dr. Hulda Clark Newsletter in UK References Clark HR. The Cure for All Cancers. San Diego, CA: ProMotion Publishing, 1993. Roberts LS. Presidential address: The cure for all diseases. Journal of Parasitology 85:996-999, 1999. Clark HR. The Cure for All Diseases. San Diego, CA: New Century Press, 1995. Promoters of alternative therapy devices give undertakings. News release, Nov 4, 1999. ACCC Web site, accessed Nov 9, 1999. Holmes S. Woman charged with practicing medicine illegally: Former Brown County resident arrested in California in case that dates back six years. Herald-Times, Bloomington, Indiana, Oct 4, 1999. Fleischer J. Former resident arrested in California. Brown County Democrat, Oct 6, 1999. Huffman AM. Probable cause affidavit. May 25, 1993.\ Hinnefield S. Judge says delay in arrest, prosecution of alternative health practitioner was too long Hoosier Times, April 19, 2000. Barrett vs. Mercola. Civil action No 2000-C-2524. Court of Common Pleas. Lehigh County, Pennsylvania, Filed Oct 3, 2000. Barrett et al vs Clark et al. Verified complaint for damages for libel, libel per se, and conspiracy to commit libel. Superior Court of the State of California, County of Alameda. Filed Nov 3, 2000. Crabtree P, Dibble S. BioPulse to sell its cancer lab in Tijuana. San Diego Union-Tribune, Feb 17, 2001.

http://www.quackwatch.com/01QuackeryRelatedTopics/Cancer/clark.html

-- Martin Thompson (mthom1927@aol.com), March 06, 2001.


Hulda Clark may be a quack. However, she is not the only one questioning the connection between HIV and AIDS. Even Luc Montagnier, the man who first identified what is now called HIV, does not regard HIV alone as sufficient to cause AIDS and he is now in active research for "co-factors," things which, in the presence of HIV, would then lead to AIDS--and without which AIDS would *not* happen, regardless of the presence of HIV.

-- L. Hunter Cassells (mellyrn@nist.gov), March 07, 2001.

FOOT & MOUTH DISEASE, EPIDEMIOLOGIC HISTORY

A ProMED-mail post ProMED-mail, a program of the International Society for Infectious Disease

Date: 7 Mar 2001 Source: Rediff, 7 Mar 2001 [edited]

A strain of the Foot-and-Mouth Disease (FMD) virus, responsible for causing one of the most contagious animal diseases, first appeared in northern India a decade ago, a newspaper report said in London.

The virus responsible for the current outbreak of FMD in British animals, reached Britain after a 10-year spread across the Middle East, Asia and the southern tip of Africa, The Times quoted an analysis published in Veterinary Record by a team from Pirbright Laboratory of the Institute for Animal Health.

It said the pan-Asia strain first appeared in northern India in 1990 and spread to Saudi Arabia, probably through the trade in live sheep and goats, and then into neighboring countries. By 1996, it was in Turkey, from where it reached Greece and Bulgaria.

From India it spread east and west -- to Nepal in 1993 and 1994, Bhutan in 1998, Tibet and Hae in China in 1999. Pan-Asia's final port of call before reaching Britain was South Africa, near Durban, the report said. Its 2 biggest conquests in the far east were Japan and Korea. Japan had been free of FMD since 1908, and Korea since 1934 and both have strict rules covering animal and meat imports.

According to Prof Chris Bostock, director of the Institute for Animal Health, the disease shows a preference for pigs which leads to a massive production [viral replication] of itself.

--- ProMED-mail

-- Andre Weltman (aweltman@state.pa.us), March 09, 2001.


Date: Thu, 8 Mar 2001 22:53:16 -0500 (EST) From: ProMED-mail Subject: PRO/AH> Foot & mouth disease, antiquated control (03)

FOOT & MOUTH DISEASE, ANTIQUATED CONTROL (03)

A ProMED-mail post ProMED-mail, a program of the International Society for Infectious Disease

[1] Date: 6 Mar 2001 From: O. Hotz de Baar

[From a previous post:"It seems to me that with the enormous increase in movement of people and animals that takes place, the concept of controlling FMD by the elaborate rituals to assure FMD-free countries is no longer tenable or appropriate. What is wrong with a vaccination program?]

This is being discussed in some depth elsewhere, but perhaps with less accurate information than can be obtained here. Were a lifetime vaccine giving near 100% protection available this would no doubt be the easy option. Unfortunately as far as I (and others) can glean the available vaccines give only short-term (under a year) and partial protection; there are no multi-strain vaccines available.

Posts here have said that animals can excrete live virus for a number of years after infection, so any infected animals, either because they recovered naturally or vaccination curtailed symptoms, may infect un-vaccinated animals for some time. That would require vaccination of all stock once or twice a year.

To be honest, I doubt whether this could be reliably achieved UK-wide for the many years it would require for all excretors to leave the system. More likely one would be faced with regular scares of small outbreaks for a decade or even more. Furthermore, such a regime would not protect susceptible wildlife (particularly deer) that now share farmland with stock all over the UK.

I also draw to your attention the fact that FMD is spectacularly infectious and particularly unpleasant. Whilst the present tragedy in the UK is extremely distressing to farmers (and I might add a significant part of the non-farming population), so far the number of animals culled is only a miniscule portion of the national herd. It should also be pointed out that it is the first significant outbreak since 1967, and other countries have been more successful in maintaining FMD-free status.

As far as I know, the US has been free since the 1920's and Australia and new Zealand have been similarly effective at excluding the disease. It is thus clear that maintaining FMD-free status is a reasonable, even sensible, long-term technique.

It has become clear that the UK has been importing significant animal products from areas where FMD is known to be endemic. Argentina, South Africa, and even Botswana have been known to supply the UK. Controls at ports and airports are slack; figures of 1400 kg of local meat being found on passengers arriving from Ghana have been quoted.

Contrast that to the strict and rigorous controls in the US, Australia and New Zealand. It is thus astonishing that the UK has only had one significant outbreak since 1967. I think it is highly likely that very many in the UK will demand the banning of animal products from countries where FMD is endemic.

The contrast between the continued long-term export of meat products from countries where FMD is endemic and the immediate banning of all UK produce almost world-wide after one or two cases has been noted. The banning (which is already in place in many countries as I understand it) of importation of animal products from countries where FMD is endemic would put further pressure on these countries to eradicate the disease (possibly with outside assistance).

There can be little doubt that this would be beneficial to worldwide animal health, animal welfare, and the economies of those countries suffering from the ravages of FMD, many of whom have many small peasant farmers, to whom FMD must be particularly devastating.

---

O. Hotz de Baar, S. England, UK

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[2] Date: 6 Mar 2001 From: Charles H. Calisher

As expected, I have received many messages which together underline the complexity of the epidemiology and politics of foot-and-mouth disease (FMD). It is clear that there are many important and complex factors, including numerous viruses, various weather conditions, geography, customs, religions, politics, money and outdated attitudes. I can scarcely say I understand all this, but I will keep trying. I summarize below all messages received (no attribution provided, but I assure the readers that I did not fabricate them). [NB: Words in brackets are those of Charles H. Calisher.]

1. One of the main reasons vaccination was suspended about 10 years ago is that countries such as the US and Japan did not accept meat from vaccinated animals. Hence the trouble.

2. I sympathize with your call for a WHO-like group to oversee livestock, but would point out that public-choice economics suggests that some such people will always look the other way, as there is no institutional check on their behavior and saintly professional types are rare in any kind of bureaucracy. WHO, for example, just published an index of national health care systems that called the US system most responsive to patient needs, but ranked it very low overall because it wasn't equitable enough. The index had been constructed to heavily weight equity. Apparently the group's organizational culture prefers that everyone get equally lousy care. [I think WHO was simply being subjective in this regard.]

3. The use of ring vaccination [i.e., vaccinating susceptible animals surrounding the known infected focus, sort of a "cordon sanitaire"] in conjunction with a slaughter policy successfully eradicated FMD from Western Europe and most of [what was then colonial] Africa . As a consequence, research on vaccines in the UK was downgraded because FMD was no longer considered a threat. [Many of us know outstanding British FMD scientists who became what is known as "redundant" and migrated to the US] The US does not have an abiding interest in FMD. [Not true, but the U.S. does not have an extensive international mission in this regard. These viruses are included in routine research studies and diagnostics done at the USDA's Plum Island Animal Disease Center. In fact, (from the PIADC web site ): "In the decade after World War II, outbreaks of foot-and-mouth disease in Mexico and Canada led Congress to establish USDA's Plum Island Animal Disease Center to keep America safe, but ready for the worst scenario: the introduction of this or other potentially devastating foreign animal diseases."]

US vets even persisted in calling it Hoof-and-mouth disease until very recently. [The Brits might now consider calling it "Foot-in- Mouth disease] The re-emergence of FMD is a consequence of the globalization of trade and the cheap food policies adopted by European governments after WWII. I doubt that the current epidemic in the UK will bring about a change in public opinion sufficient to support the investment in vaccine development required. Unfortunately the viruses causing this disease are antigenically highly variable.

At the recent International Congress of Virology held in Sydney, Fred Brown and Marc van Regenmortel described a very promising development in FMDV vaccine research. The peptide vaccine developed by Fred and his group at Pirbright is the only anti-viral peptide vaccine that is practical, and Marc's recent modification of it has enhanced its stability beyond expectation. I don't know whether any company is interested in developing this approach further.

4. There is a widely used and effective vaccine for FMD. It is used in countries that have active eradication campaigns in place. There are also vaccines prepared from several different strains of FMD that could be used to protect against the pan-Asia strain of FMDV. As far as I know, the UK has never utilized vaccines to FMD, even in the 1967 outbreak. The reason for this include: (1) in the past the vaccines had occasionally been shown to be contaminated with live virus, so those vaccines themselves could cause FMD (this has been largely controlled recently, and I am sure that vaccines made by the large multi-nationals are completely safe); (2) vaccinated animals may be difficult to distinguish serologically from previously infected animals (eliminating serology as a method of identifying infected animals); (3) while attempting to "emergency vaccinate" animals, the vaccination teams can spread disease; (4) and (in my opinion) most importantly, vaccinated animals may be come infected, and show less severe signs of disease, despite shedding virus, thus prolonging an outbreak by allowing infected animals to escape ready visual detection. Efforts are being directed toward development of more rapidly acting and more effective vaccines, as well as towards learning more about infection, with hopes of developing therapeutics that could help to reduce shedding, and learning more about viral ecology, spread, evolution, and host range. [Of course, one need not be concerned about live virus in a vaccine prepared from antigens unassociated with infectious materials.]

6 [[5?]]. To help celebrate the 100th anniversary of the field of virology, celebratory meetings were held in Greifswald, Germany, and Amsterdam, The Netherlands. Marian Horzinek and I served as Editors of the presented papers for a Special Issue of Archives of Virology (Springer-Verlag, Vienna/New York, 1999). It was on the Island of Reims, just outside Greifswald, where Friedrich Loeffler and his associates did the first work with FMD. Doesn't look to me as though much has changed in 100 years. This is still a disease with a political basis. What may be needed is more funding of the right people, which is not a new concept.

---

Charles H. Calisher, Ph.D., Colorado State University, Fort Collins, Colorado, U.S.A.

-- Andre Weltman (aweltman@state.pa.us), March 09, 2001.



BB C

Friday, 9 March, 2001, 13:41 GMT 'Second wave' of disease hits farms

Infected sheep are passing disease to cattle Two weeks after the ban on animal movements to try to curb the spread of foot-and-mouth disease, a "second wave" of new cases has been identified.

It had been hoped that new cases would start to tail off, as foot-and-mouth normally incubates in livestock for a maximum of 14 days.

But 13 more cases have been confirmed so far on Friday, bringing the total number of UK outbreaks to 120.

The figure compares to 185 cases after the same length of time during the 1967 crisis.

Farmers had been hoping that the restrictions on the movement of livestock during the crisis would be eased on Friday.

But Chief Veterinary Officer, Jim Scudamore, said tight restrictions on livestock movements and other activities that risked spreading the disease were absolutely essential.

"These restrictions must be retained until we are sure the outbreak is over," he said.

"To relax the controls too early could lead to a further deterioration in the situation."

Mr Scudamore was speaking after a regular weekly meeting with farmers' leaders and members of the meat and livestock industry.

He said there had been signs that some people felt that the problem was over and that the tight controls were no longer required.

"This could have caused some complacency in observing the rules," he said.

The new outbreaks included some in previously unaffected areas and three in Scotland, bringing the country's total to 16.

Ministry of Agriculture officials said the latest confirmed cases included detection of the disease among cattle and sheep at a farm in Arthuret in Cumbria, a farm in Derbyshire and a farm in Shebbear in Devon.

The National Assembly for Wales said the country's fifth case was confirmed at the Tawny Owl Animal Park in Painscastle, Powys.

The sheep and cattle which are at the park will have to be slaughtered within 24 hours.

Lambing fears

Farmers fear pregnant animals currently left out in the open will suffer unless they can be brought back to farms to give birth.

They want the government to allow limited movement of pregnant sheep, cattle and pigs which are stranded in open fields, often short of food.

The biggest problem now presenting itself across the UK is that the disease seems to be spreading most rapidly among cattle which have come into contact with sheep carrying the virus.

Mr Scudamore said 89,000 animals had now been earmarked for slaughter - and that 61,000 of them had already been culled.

Restrictions were still in place on 144 farms pending ongoing investigations, while 68 premises had already been classified as "dangerous contacts", with animals being destroyed.

Royal visit cancelled

The crisis is continuing to affect sporting fixtures across the country.

The decision to postpone Cheltenham's prestigious horse racing festival could cost up to £10m in lost trade if the event does not go ahead at a later date.

Some horse racing fixtures have resumed.

But the Queen Mother's expected visit to Sandown Park in Surrey was cancelled on Friday as part of the course was waterlogged.

The GMB union warned that more than 52,000 jobs in abattoirs and meat processing centres are at risk because of the continuing crisis.

-- Rachel Gibson (rgibson@hotmail.com), March 09, 2001.


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